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Primary RegistryProtocol numberPublic titleScientific titleType of studyRecruitment statusLast updated
LBCTR2023115331BO42451A RANDOMIZED DOUBLE-BLIND PHASE IIA STUDY EVALUATING THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB AS ADJUNCT TREATMENT IN PREVENTION OF VASO-OCCLUSIVE EPISODES (VOE) IN SICKLE CELL DISEASE (SCD)A RANDOMIZED DOUBLE-BLIND PHASE IIA STUDY EVALUATING THE EFFICACY, SAFETY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CROVALIMAB AS ADJUNCT TREATMENT IN PREVENTION OF VASO-OCCLUSIVE EPISODES (VOE) IN SICKLE CELL DISEASE (SCD)InterventionalRecruiting06/04/2023
LBCTR2025075755CR: 3/2023EFFICACY OF 10 DAYS HIGH-DOSE AND DOUBLE-DOSE RABEPRAZOLE-BASED CONCOMITANT THERAPY FOR HELICOBACTER PYLORI ERADICATION AMONG LEBANESE POPULATION: A PILOT RANDOMIZED CONTROLLED TRIALEFFICACY OF 10 DAYS HIGH-DOSE AND DOUBLE-DOSE RABEPRAZOLE-BASED CONCOMITANT THERAPY FOR HELICOBACTER PYLORI ERADICATION AMONG LEBANESE POPULATION: A PILOT RANDOMIZED CONTROLLED TRIALInterventionalComplete20/07/2025
LBCTR2022055019CJDQ443B12301Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung CancerA Randomized, Controlled, Open Label, Phase III Study Evaluating the Efficacy and Safety of JDQ443 Versus Docetaxel in Previously Treated Subjects With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung CancerInterventionalSuspended28/03/2022
LBCTR2023015151CLOU064C12301Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple SclerosisA Randomized, Double-blind, Double-dummy, Parallel-group Study, Comparing the Efficacy and Safety of Remibrutinib Versus Teriflunomide in Participants With Relapsing Multiple Sclerosis, Followed by Extended Treatment With Open-label RemibrutinibInterventionalPending14/10/2022
LBCTR2023035313CAIN457C22301Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)A Randomized, Parallel-group, Double-blind, Placebo-controlled, Multicenter Phase III Trial to Evaluate Efficacy and Safety of Secukinumab Administered Subcutaneously Versus Placebo, in Combination With a Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)InterventionalPending22/03/2023
LBCTR2024065610CAIN457C22301E1Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)A Multi-center, Open-label Extension Study of Subcutaneous Secukinumab to Evaluate the Long-term Safety and Tolerability in Polymyalgia Rheumatica (PMR)InterventionalPending14/06/2024
LBCTR2019020198SEG101B2201Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease PatientsA Phase 2,Multicenter,Open-Label Study to Assess Appropriate Dosing and to Evaluate Safety of Crizanlizumab,With or Without Hydroxyurea/Hydroxycarbamide,in Sequential,Descending Age Groups of Pediatric Sickle Cell Disease Patients With Vaso-Occlusive CrisisInterventionalRecruiting20/02/2019
LBCTR2022095114CLEE011A2412BRoll-over Study to Allow Continued Access to RibociclibA Post-trial Access Roll-over Study to Allow Access to Ribociclib (LEE011) for Patients Who Are on Ribociclib Treatment in Novartis-sponsored StudyInterventionalComplete17/08/2022
LBCTR2019060244CSEG101A2301Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients ( STAND)A Phase III, Multicenter, Randomized, Double-blind Study to Assess Efficacy and Safety of Two Doses of Crizanlizumab Versus Placebo, With or Without Hydroxyurea/ Hydroxycarbamide Therapy, in Adolescent and Adult Sickle Cell Disease Patients With Vaso-Occlusive Crises (STAND) InterventionalComplete11/06/2019
LBCTR2021034776CKJX839C12301Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial HypercholesterolemiaTwo Part (Double-blind Inclisiran Versus Placebo [Year 1] Followed by Open-label Inclisiran [Year 2]) Randomized Multicenter Study to Evaluate Safety, Tolerability, and Efficacy of Inclisiran in Adolescents (12 to Less Than 18 Years) With Heterozygous Familial Hypercholesterolemia and Elevated LDL-cholesterol (ORION-16)InterventionalComplete25/03/2021
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