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| LBCTR2019090195 | GBT440-007 | Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease | A Phase 2a, Open-label, Single and Multiple Dose Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Exploratory Treatment Effect of GBT440 in Pediatric Participants With Sickle Cell Disease | Interventional | Recruiting | 19/02/2019 |
| LBCTR2019080217 | GBT440-031 | Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) | A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study of Voxelotor Administered Orally to Patients With Sickle Cell Disease | Interventional | Complete | 16/07/2020 |
| LBCTR2019080216 | GBT440-034 | Study to Assess the Effect of Long-term Treatment With GBT440 in Participants Who Have Completed Treatment in Study GBT440-031 | An Open Label Extension Study of GBT440 Administered Orally to Patients With Sickle Cell Disease Who Have Participated in GBT440 Clinical Trials | Interventional | Other | 27/03/2019 |
| LBCTR2020063513 | GBT440-038 | Open-Label Extension of Voxelotor | An Open-Label Extension Study of Voxelotor Administered Orally to Participants with Sickle Cell Disease Who Have Participated in Voxelotor Clinical Trials | Interventional | Pending | 12/06/2020 |
| LBCTR2021024523 | GC1801 | Phase 3 study to evaluate the efficacy and safety of human plasma-derived fibrinogen concentrate (FIB Grifols) in subjects with congenital afibrinogenaemia and severe hypofibrinogenemia | A prospective, multicenter, open-label, single-arm study to evaluate the efficacy and safety of human plasma-derived fibrinogen concentrate (FIB Grifols) in subjects with congenital afibrinogenaemia and severe hypofibrinogenemia requiring either ondemand treatment for acute bleeding or surgical prophylaxis | Interventional | Pending | 14/07/2020 |
| LBCTR2019121361 | HD2305 | Preoperative Chlorhexidine Gluconate Bathing Could Prevent Post-obstetric and gynecologic Surgical-site Infections: A Pilot for a Randomized Controlled Trial | Preoperative Chlorhexidine Gluconate Bathing Could Prevent Post-obstetric and gynecologic Surgical-site Infections: A Pilot for a Randomized Controlled Trial | Interventional | Pending | 24/12/2019 |
| LBCTR2020043459 | HDF 1632 | The effect of confinement on the mental health of individuals during the COVID-19 pandemic: an online survey | The effect of confinement on the mental health of individuals during the COVID-19 pandemic: an online survey | Observational | Pending | 16/04/2020 |
| LBCTR2019020197 | ICL670F2202 | Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload ( CALYPSO) | A randomized, open-label, multicenter, two arm, phase II study to evaluate treatment compliance, efficacy and safety of an improved deferasirox formulation (granules) in pediatric patients with iron overload | Interventional | Complete | 20/02/2019 |
| LBCTR2020093402 | IMR-BTL-201 | A Phase 2 Study to Evaluate the Safety and Tolerability of IMR-687 in Subjects with Beta Thalassemia | A Phase 2 Study to Evaluate the Safety and Tolerability of IMR-687 in Subjects with Beta Thalassemia | Interventional | Pending | 24/02/2020 |